The laboratory was established in September 2018 in the structure of the Department of Pediatrics. The main task of the laboratory is fundamental and applied developments in the following areas: infectious diseases, immunology and vaccination in children.
Moskaleva Ekaterina Vladimirovna, PhD, Research оfficer
Kharkhorina Anastasia Anatolyevna, PhD, Research оfficer
Kazantseva Ekaterina Dmitrievna, Postgraduate Student, Junior Researcher
Anna Mikhailovna Tryapkina, Research Assistant
Three of the five employees are young scientists.
• fundamental and applied aspects of current and socially significant infections in children: respiratory infections, including COVID-19 and post-COVID syndrome, HIV infection, herpesviral diseases, as well as issues of immunology of infections and vaccination in children Development and implementation of prognostic, preventive and personalized strategies for the diagnosis and treatment of infectious diseases in childhood;
• аssessing adherence and effectiveness of childhood vaccination, and developing personalized approaches aimed at improving immunoprophylaxis;
• pathogenetic mechanisms of the formation of health disorders and development of children born to HIV-infected mothers;
• use of proteomics, metabolomics and genomics in these areas; development and implementation of non-invasive and minimally invasive methods for the diagnosis and treatment of infectious diseases.
The laboratory cooperates with Russian scientific, educational and medical institutions: Children's Research and Clinical Center for Infectious Diseases of the Federal Medical and Biological Agency (St. Petersburg); Research Institute of Pediatrics and Children's Health Protection «Petrovsky National Research Center of Surgery», Institute of Motherhood and Childhood of the Federal State Autonomous Educational Institution of Higher Education «N.I. Pirogov Russian National Research Medical University» of the Ministry of Health of the Russian Federation, Moscow; Federal Research Center for Fundamental and Translational Medicine, Novosibirsk; Krasnoyarsk State Medical University, Federal Research Center «Krasnoyarsk Science Center» of the Siberian Branch of the Russian Academy of Sciences, Krasnoyarsk; North-Eastern Federal University, Yakutsk; Chita State Medical Academy; Pacific State Medical University, Vladivostok, Gomel State Medical University, Irkutsk Regional Infectious Diseases Clinical Hospital; Irkutsk Regional Center for the Prevention of AIDS and Infectious Diseases; pediatric health care institutions in Irkutsk and others.
In 2018-2024, according to the areas of work of the laboratory, the staff published more than 90 papers, including three monographs, registered three patents, made over 70 reports at conferences and congresses, including foreign ones, read 12 popular science messages for the population, developed educational programs for advanced training of doctors on current childhood infections with an in-depth course of vaccination.
Scientific works have been published in leading peer-reviewed journals: Acta Biomedica Scientifica, Issues of Practical Pediatrics, Journal of Infectology, Pediatric Infections. Infectious diseases. Bulletin of Experimental Biology and Medicine, Cell and Tissue Biology, Free Radical Biology & Medicine, Infection and Immunity. Siberian Scientific Medical Journal, Yakut Medical Journal, Epidemiology and Vaccine Prevention, Pacific Medical Journal, BMJ Paediatrics Open, Immunology.
In close cooperation with other departments of the Scientific Center, fundamental scientific topics and search technologies, candidate and doctoral dissertations are carried out.
Together with the Ministry of Health of the Irkutsk Region, two interdepartmental multicenter projects of scientific and applied importance were implemented: to study adherence to vaccination in children and to assess the intensity of population immunity to vaccine-preventable infections.
Under the auspices of the Ministry of Education and Science, the Union of Pediatricians of Russia, the Scientific Center for Family Health and Human Reproduction Problems and other participating organizations, since 2019, the laboratory has been holding Russian conferences with international participation twice a year, which serve as a broad information platform for discussing topical issues of infectious diseases and vaccination in children. Leading specialists of the Russian Federation in the field of pediatric infectology and vaccine prophylaxis, and young scientists from Moscow, St. Petersburg, Krasnoyarsk, Yuzhno-Sakhalinsk, Yakutsk, Chita, Irkutsk and foreign countries take part in the events with reports.
