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Gynecological Endocrinology Laboratory

Danusevich Irina Nikolaevna

Head of the Laboratory since 2017, Doctor of Medical Sciences

Данусевич Ирина Николаевна.jpg
    The Laboratory of Gynecological Endocrinology was established in 2003. Initially, the Laboratory was headed by Dr. Sc. (Med.), Professor Suturina L.V., from 2011 until 2015, Dr. Sc. (Med.) Labygina A.V. managed the laboratory.

The main research areas:

  • study of the pathogenetic mechanisms of formation of reproductive health disorders of the family, considering age, gender and ethnic characteristics of the population of Eastern Siberia, and the development of new medical technologies for maintaining reproductive potential and restoring reproductive health (patterns of mutual regulation of the hormonal status of the body and lipid peroxidation, the state of the genital tract microbiome in case of reproductive disorders are studied);

  • study of epidemiological and molecular-biological characteristics of neuro-endocrine diseases in Eastern Siberia and development of effective methods of diagnosis, treatment and prognosis.

In particular, the laboratory staff implemented a large-scale project to assess the prevalence of infertility in marriage, PCOS and its phenotypes in various age and ethnic groups, studied the epidemiology of the main hormone-dependent gynecological diseases in Eastern Siberia, identified the most informative molecular markers and predictors of reproductive disorders in women and men. The laboratory conducts clinical studies of the effectiveness and safety of new drugs and implements innovative educational programs aimed at maintaining the reproductive potential of the population.

The laboratory cooperates with Russian scientific institutes (Irkutsk, Moscow, St. Petersburg, Novosibirsk, Krasnoyarsk, Ulan-Ude, Chita, Kemerovo, etc.), higher professional education institutions (Irkutsk, Chita, Kemerovo, etc.) and practical healthcare institutions (Irkutsk, Ulan-Ude). Along with this, cooperation is carried out with foreign scientific institutes - The State University of New York (SUNY); Penn State University College of Medicine; USC Keck School of Medicine; Hacettepe University School of Medicine.

Since 2005, the laboratory of gynecological endocrinology has been the initiator and main organizer of the traditional scientific and practical conference "Fundamental and Applied Aspects of Reproduction". The purpose of the conference is to contribute to the expansion of theoretical and conceptual representations on the most important fundamental issues of reproduction; induce the development of new scientific research; to promote the popularization and promotion of scientific knowledge and achievements, to expand international scientific cooperation of specialists in this field, as well as to promote the implementation of the results of modern scientific research in practical health care.

During the laboratory’s activities, employees took part in the following grants: a grant from the Regional Public Fund for the Promotion of Domestic Medicine in the nomination “Biomedical Sciences” (2007-2009); Grant of the European Society of Contraception (ESC) (2016) for the course “The best practice for providing contraception in adolescents: training course for Ob & Gyn specialists” (2016), Grant of ESC (2018) “Stigma and discrimination against people living with HIV (PLHIV) ), by obstetrician-gynecologists and a training program to reduce discrimination”.

The results of the researches are reflected in 24 patents and in more than 350 articles in leading Russian and foreign publications: Obstetrics and gynecology; Human ecology; Expert Review of Molecular Diagnostics; Acta Biomedica Scientifica; Advances in Obesity, Weight Management and Control; Bulletin of Experimental Biology and Medicine; Reproductive Sciences; Medical Hypotheses; Minerva Ginecologica et al.

 Laboratory staff has defended 3 doctoral and 4 candidate’s dissertations, prepared more than 30 graduate students and applicants for academic degrees in the specialties.